[Here there be links galore!]
Reading Butler, my own scifi will have my own humans and other species 'uplift' themselves, Brin-style, in order to survive and thrive through and beyond the rigors of space, time, cyberspace, and hyperspace...
My humans will have to use both natural (bio/chemical) and artificial means to change their bodies.
Just like my Aturans had to inject, digest, aerosol, and applying topically variations of medicines, antihistamines, accelerants, depressants, astringents, supplements, vitamins, and hormonal in order to survive on our world, we humans as a species will have to learn to do the same.
